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ATCC
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Charles River Laboratories
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Image Search Results
Journal: Cell reports
Article Title: Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity
doi: 10.1016/j.celrep.2021.108948
Figure Lengend Snippet: (A and B) Combination treatments of fascin inhibitors with anti-PD-1 and anti-CTLA-4 antibodies synergistically increase the overall survival of mice bearing 4T1 mouse triple-negative breast tumor cells. (A) Scheme of treatments. (B) Overall survival data for the four groups of mice with different treatments (n = 8 or 10). (C and D) Combination treatments of fascin inhibitors with anti-PD-1 and anti-CTLA-4 antibodies synergistically increase the overall survival of mice bearing EMT6 mouse triple-negative breast tumor cells. (C) Growth of primary tumors. Data are presented as mean ± SEM (n = 8 or 9). (D) Overall survival data for the four groups of mice with different treatments (n = 8 or 9). (E) Combination treatments of fascin inhibitors with anti-PD-1 and anti-CTLA-4 antibodies synergistically increase the overall survival of mice bearing LLC mouse lung cancer cells (n = 8–10). (F) Fascin inhibitors with anti-PD-1 and anti-CTLA-4 antibodies synergistically increase the overall survival of mice bearing Pan02 mouse pancreatic cancer cells (n = 7 or 8). (G) NP-G2–044 with anti-PD-1 and anti-CTLA-4 antibodies increase the overall survival of mice bearing PNEC30 mouse prostate cancer cells (n = 8 or 9).
Article Snippet: To investigate whether this synergistic effect might be limited to 4T1 tumors, we used
Techniques:
Journal: Cell reports
Article Title: Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity
doi: 10.1016/j.celrep.2021.108948
Figure Lengend Snippet: KEY RESOURCES TABLE
Article Snippet: To investigate whether this synergistic effect might be limited to 4T1 tumors, we used
Techniques: Control, Recombinant, Plasmid Preparation, shRNA, Membrane